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Monday, February 3, 2014

Genetically Altered Humans?


I love to see progress in the Science and Technology fields, but this gave me the creeps.  Do we really want the scenes from science fiction  novels to become our reality?  Don't we have enough number of mutants walking our Earth already? Just look inside the LGBT community.  What do you see?

Right now, whatever the scientists are telling us, all sounds good ... that this procedure would eliminate the disease-carrying genes, thus freeing new born humans from various kinds of ills. But, one has to wonder what the future holds for the genetically modified humans and the other "normal" humans they might share their DNA with at a later point in their adult lives.

David DiSalvo writing at Forbes:
....The Era Of Genetically-Altered Humans Could Begin This Year.  By the middle of 2014, the prospect of altering DNA to produce a genetically-modified human could move from science fiction to science reality.  At some point between now and July, the UK parliament is likely to vote on whether a new form of in vitro fertilization (IVF)—involving DNA from three parents—becomes legally available to couples. If it passes, the law would be the first to allow pre-birth human-DNA modification, and another door to the future will open.

The procedure involves replacing mitochondrial DNA (mtDNA) to avoid destructive cell mutations. Mitochondria are the power plants of human cells that convert energy from food into what our cells need to function, and they carry their own DNA apart from the nuclear DNA in our chromosomes where most of our genetic information is stored. Only the mother passes on mtDNA to the child, and it occasionally contains mutations that can lead to serious problems.

The U.S. is not nearly as close to approving mtDNA replacement as the UK seems poised to do; the U.S. Food and Drug Administration will start reviewing the data in earnest in February.  Among the concerns on the table is whether the mtDNA donor mother could be considered a true “co-parent” of the child, and if so, can she claim parental rights?

Even though the donor would be contributing just 0.1 percent of the child’s total DNA (according to the New Scientist report), we don’t as yet have a DNA benchmark to judge the issue. Who is to say what percentage of a person’s DNA must come from another human to constitute biological parenthood?

Other scientists have raised concerns about the compatibility of donor mtDNA with the host nucleus and believe the push to legalize human trials is premature. By artificially separating mtDNA from the nucleus, these researchers argue, we may be short-circuiting levels of genetic communication that we’re only beginning to fully understand.....

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